Study reveals safety of long-term daily cannabidiol use in healthy dogs

A substantial stride in this realm as there is still a lot to uncover surrounding CBD use in puppies

Mars Petcare has disclosed results from a security study displaying that a every day oral dose of cannabidiol (CBD) at the studied concentration and duration was properly-tolerated by a cohort of clinically healthier grownup dogs.

“I’m heartened to see this analyze on the safety of CBD for pet health and fitness. We proceed to get inquiries from pet owners on whether it is safe and sound to give their animals CBD. We hope, with continued research, to be capable to offer science-centered direction our clients expect and depend on,” expressed Jennifer Welser, DVM, DACVO, chief healthcare officer of Mars Veterinary Health and fitness, in a enterprise release.1

Led by the Waltham Petcare Science Institute, the examine was part of Mars Petcare, and published in Frontiers in Veterinary Science. Its findings contributed to expanding evidence bordering the basic safety of CBD for pet dogs.

The purpose of the randomized, placebo-controlled, and blinded analyze was to both1:

  • Find out tolerance of a as soon as-day-to-day oral dose (4 mg/kg of physique weight) properly characterised, wide-spectrum THC-free of charge CBD distillate during a 6-thirty day period time period to nutritious grownup dogs.
  • Quantify the degree of CBD in the dogs’ fasted plasma, urine, and feces through the exact period.

Analyze members consisted of 40 healthful canine, together with 17 Labrador retrievers 8 beagles and 15 Norfolk terriers, randomized and well balanced throughout 2 parallel treatment teams: CBD and placebo. Scientists examined an array of wellness measures, together with biochemistry, haematology, and urinalysis, along with regular veterinary examinations, twice day by day wellbeing observations, and a everyday high-quality-of-lifetime survey. The actions ended up recorded ahead of, then after 2, 24, 10, 18, and 26 months of CBD feeding, adopted by 4 weeks of washout. CBD concentrations were calculated at the exact intervals in plasma, feces, and urine.


Mars Petcare research demonstrates protection of extensive-expression each day cannabidiol use in healthier canines. Information release. Mars Petcare. September 21, 2022. Accessed September 22, 2022. dogs